• Location: Durham, NC
  • Posted: Jan 6, 2020

Job Description

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nations top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.

Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Drs. Deborah Muoio and Paul Grimsrud invite applications for a postdoctoral fellowship position at the Duke Molecular Physiology Institute (DMPI) within the School of Medicine at Duke University (Durham, NC). The DMPI and Duke University are part of abroad and dynamic community of academic and industry scientists in the Research Triangle Park (RTP) area of North Carolina. The DMPI occupies a place of national and international leadership in the fight against major diseases and is a multi- and inter-disciplinary Institute encompassing basic and translational investigators across a variety of scientific disciplines. Our mission is to produce integrated multi-omics and physiologic profiles of chronic human diseases, and to use such profiles to develop new disease detection strategies, novel therapies, and insights into disease mechanisms.

The Postdoctoral Associate will utilize mass-spectrometry-based proteomics and metabolomics to investigate roles of protein post-translational modifications (PTMs) in regulating mitochondrial physiology and metabolic flux inheart, skeletal muscle and liver. The ideal candidate will have strong training in basic sciences and research interests in molecular mechanisms of chronic metabolic disorders or conditions suchas obesity, diabetes, cardiovascular disease and aging. Although candidates with expertise in all areas of basic science research will be considered, strong preference will be given to those with experience in in analytical chemistry, mass spectrometry, quantitative proteomics and/or systems biology. This position offers a vibrant and highly interactive academic setting in a new state-of-the-art research facility, along with NIH-sponsored funding, access to outstanding resourcesand technology platforms,strong computational support from the DMPI Computational Biology Core, and a friendly, collaborative and interdisciplinary group of colleagues in boththe clinical and basic sciences.


The candidate will have a minimum of a PhD, preferably in analytical chemistry or biochemistry.


Prior experience in proteomics is highly desirable and formal training in bioinformatics/computer science would be beneficial.

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideasan exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

Duke Health

705 Broad Street
Durham, NC 27708

Phone: (919) 684-5600

Fax: (919) 684-5600