Dana-Farber Cancer Institute

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The laboratory of Dr. Alessandra Biffi at the Dana-Farber Cancer Institute, is seeking an energetic, efficient, and resourceful person who will participate to laboratory operations, and provide critical support to the principal investigator (PI) and her team. Requirements The successful candidates will work on projects...

The Dhe-Paganon Lab and Longwood Center for Structural & Chemical Biology at the Dana-Farber Cancer Institute is seeking a research technician to join the scientific team. This individual will collaborate with other scientists and cross-functional team members in order to advance mechanism and drug discovery projects. They will work independently as well as part of a multi-disciplinary research team to design & execute experiments and analyze & interpret results for ongoing chemical and structural biology research. Primary responsibilities include performing recombinant protein expressions and purifications and/or invitro biophysical, biochemical, and crystallization assays and screens. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented...

An immediate opening for a research technician is available in Dr. William Shih’s lab. We aim to develop DNA nanostructure-based tools for applications such as cancer immunotherapies and research analysis. Successful candidates will work with an interdisciplinary team of scientists experienced in biochemistry, DNA nanotechnology, and cancer immunotherapy. The successful candidate will participate and learn the process of an interdisciplinary project using multiple technologies. We are seeking an enthusiastic and self-motivated candidate with biochemistry training who is willing to learn multi-discipline approaches. The individual will also assist in daily laboratory operations and organization. We are looking for candidates with a minimum of two-year availability. Candidates with laboratory technician experience and those potentially interested in a long-term position are encouraged to

The Department of Data Sciences at Dana-Farber Cancer Institute is seeking a Scientific Program Manager to lead the efforts for the Human Tumor Atlas Network (HTAN), a high profile "Moonshot" project funded by the National Cancer Institute (NCI). We are seeking an exceptional candidate who has deep experience in coordinating scientific consortia, and managing and processing data for a distributed network of research centers.   Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our...

The Center for Protein Degradation (CPD) seeks a highly motivated individual to join the team as a SCIENTIST who will work on various structural biology and biochemical projects focused on the development of molecular glues and degrader molecules. Join our highly interactive team of scientists and technicians to work on testing and creating new avenues of therapeutic intervention. Dana-Farber Cancer Institute (DFCI) and Deerfield Management have entered a multi-year collaboration to create the Center for Protein Degradation (CPD) at DFCI led by Drs. Fischer and Gray.  The goals of the Center for Protein Degradation are to create a next-generation protein degrader platform and interrogate and advance a large portfolio of protein degrader targets.   This is an exceptional opportunity to join a newly founded research center that is pushing the boundaries of targeted protein degradation research and accelerating the translation of basic science into clinical solutions. This individual...

The Center for Protein Degradation (CPD) seeks a highly motivated individual to join the team as a SCIENTIST who will work on various structural biology and biochemical projects focused on the development of molecular glues and degrader molecules. Join our highly interactive team of scientists and technicians to work on testing and creating new avenues of therapeutic intervention. Dana-Farber Cancer Institute (DFCI) and Deerfield Management have entered a multi-year collaboration to create the Center for Protein Degradation (CPD) at DFCI led by Drs. Fischer and Gray.  The goals of the Center for Protein Degradation are to create a next-generation protein degrader platform and interrogate and advance a large portfolio of protein degrader targets.   This is an exceptional opportunity to join a newly founded research center that is pushing the boundaries of targeted protein degradation research and accelerating the translation of basic science into clinical solutions. This individual...

Research Scientist position available in a laboratory at Dana-Farber Cancer Institute, an affiliate of Harvard Medical School, using systems biology, molecular biology, single-cell, bioinformatics, and computational approaches to understand virus-host interactions and disease mechanisms in HIV infection and associated comorbidities including accelerated aging, immune dysregulation, neurological disease, and cancer. Bioinformatics scientists work closely with wet lab scientists to generate, analyze, and interpret large-scale datasets using various software for data integration, network prediction, pathway analysis, and machine learning. Ideal candidates will have a strong background in relevant areas of molecular biology and biomedical science and perform wet lab experiments in addition to bioinformatics and computational analysis. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and...

Research Scientist Position available to join our human antibody discovery and chimeric antigen receptor (CAR) T-cell cancer therapy programs in the Marasco Lab within the Department of Cancer Immunology and Virology. The research scientist will lead our efforts in developing CAR T cell factories and examining the combinatorial effect of CAR T with expression of the immune modulator antibodies on inhibiting tumor growth in vitro and in vivo. The focus of our efforts will be against ovarian cancer (OV) or triple negative breast cancer (TNBC). Requirements Working with a team of dedicated research staff including computational, cellular, molecular and structural biologists and virologists, each research scientist will be responsible for designing and executing in vitro and in vivo experiments for their designated disease area. S/he will generate cancer target specific CAR constructs, create CAR T-cells, carry out in vitro assays to test and optimize their biological activities,...

The Knowledge Systems Group at Dana-Farber Cancer Institute is seeking a Scientist (PhD new grads encouraged to

Dipanjan Chowdhury’s laboratory in Radiation Oncology is searching for a motivated Senior Research Technician. The position will focus on research in understanding the molecular biology of DNA repair. Basic understanding of biochemistry and molecular biology is necessary. This position requires excellent communication skills, close attention to detail, and consistent work habits. Responsibilities will include some aspects of laboratory management Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to...

We are seeking a Software Engineer to help build open-source software to enable precision cancer medicine.  The Knowledge Systems Group (KSG) at the Dana-Farber Cancer Institute operates at the crossroads of cancer genomics, software and medicine. Our platforms are focused on mining of cancer genomic data sets, matching patients to clinical trials, and building cloud-based infrastructure for sharing of cancer data. Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners,...

The Knowledge Systems Group in the Department of Data Sciences is looking for a summer intern that can help develop and maintain the cBioPortal as either a frontend, backend or full stack developer. The cBioPortal backend is built using Java, Spring MVC, and MySQL. The frontend is built in Typescript, React, and MobX. The cBioPortal for Cancer Genomics is an open-source software platform that enables interactive, exploratory analysis of large-scale cancer genomics data sets with a biologist-friendly interface. It integrates genomic and clinical data and provides a suite of visualization and analysis options. Currently, the cBioPortal has over 40 local installations and sees more than 30,000 unique visitors a month. We maintain a public cBioPortal instance at: https://www.cbioportal.org/, and all code is managed via GitHub at: https://github.com/cbioportal. This is a full-time, 40-hr per week paid on-site internship.  Located in Boston and the surrounding communities, Dana-Farber...

A Scientist position is open to join the Burns laboratory in the Department of Oncologic Pathology at Dana-Farber Cancer Institute. We are looking for a Scientist to provide scientific leadership to our existing and upcoming projects. Our group studies high copy number repeats in the human genome, and the biology of the retrotransposons and endogenous retroviruses that generate these sequences. We and others have shown that subsets of these normally silenced elements are expressed as a hallmark of human cancers, and that this results in somatically-acquired retrotransposon insertions in cancer genomes. We aim to more fully characterize this phenomenon; to probe its consequences for cancer biology using models of cancer growth and tumor immunology; and to leverage our understandings to inform cancer detection and treatment. The lab is moving from Johns Hopkins School of Medicine, and the successful candidate will be one of the first to establish the group at DFCI. He/she will...

The staff nurse's responsibilities include assessment, planning, implementation and evaluation of nursing care for a complex patient population. The infusion nurse provides patient and family education and psychosocial and emotional support. He/she is a member of a multidisciplinary care team that requires effective communication and collaboration with co-workers and staff at the Institute, BWH, and other collaborating institutions and agencies. The infusion nurse identifies his/her own professional goals and learning needs. The role requires clinical expertise, critical thinking, collaborative practice, excellent communication skills and an understanding of the principles and practices of clinical research. The Mission, Vision and Core values of the Dana-Farber Cancer Institute are incorporated into all areas of practice. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated...

The staff nurse's responsibilities include assessment, planning, implementation and evaluation of nursing care for a complex patient population. The infusion nurse provides patient and family education and psychosocial and emotional support. He/she is a member of a multidisciplinary care team that requires effective communication and collaboration with co-workers and staff at the Institute, BWH, and other collaborating institutions and agencies. The infusion nurse identifies his/her own professional goals and learning needs. The role requires clinical expertise, critical thinking, collaborative practice, excellent communication skills and an understanding of the principles and practices of clinical research. The Mission, Vision and Core values of the Dana-Farber Cancer Institute are incorporated into all areas of practice. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated...

The Division of Population Science’s Center for Outcomes and Policy Research at Dana-Farber Cancer Institute is seeking a Statistical Programmer to collaborate with scientific investigators and other statisticians in the design and analysis of clinical trials, basic translational studies, observational data from surveys, medical records, or administrative data. Additionally, the Statistical Programmer may be tasked with data from the study of genetic markers in human populations or animal models of cancer, experiments on the development of new laboratory assays and data from population-based studies. Qualified candidates will have formal training in statistics or biostatistics and strong statistical computing skills. Researchers in the Division of Population Science’s Center for Outcomes and Policy Research aim to enhance the outcomes of interventions to prevent and treat cancer from both efficacy and cost-effectiveness perspectives. Investigations focus on optimizing the patient...

A full-time position is available for a highly motivated Research Technician to join the Translational Immunogenomics Lab (TIGL) team. The Translational Immunogenomics Lab (TIGL) within DFCI uses state-of-the-art genomic technologies to assess the response of the immune system to cancer and therapy. TIGL evaluates the latest developments in the field, implements the optimal methods for the task at hand, and invents methods when current approaches are inadequate. The current focus of TIGL is discovering patient-specific neoantigens, understanding the details and consequences of interactions between neoantigens and T cells, and

Exciting opportunity for an experienced, motivated research technician to join a translational laboratory studying various aspects of cellular adaptive immunity, especially in relation to T regulatory cell characterization, function and expansion, as well as the effects of various immune manipulations. We have a history of successfully conducting basic and preclinical experiments on new biologic agents and translating them into the clinic, and currently collaborate in clinical trials studying the adaptive use of T regulatory cells in transplant settings and in cancer. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of...

We are seeking a highly-motivated and skilled Senior Research Technician who will be responsible for providing high-level technical support for ongoing research efforts in the labs of Dr. Scott Armstrong and Dr. Kimberly Stegmaier and the Center for Pediatric Cancer Therapeutics. Our research focuses on identifying new treatment approaches for pediatric patients with cancer. The laboratory uses a variety of genomic, epigenomic, and chemical biology approaches to characterize the mechanisms that control pediatric cancer development and identify new therapeutic targets. The senior research technician will work with in vitro and in vivo models of pediatric cancers to validate new therapeutic candidates for leukemias and solid tumors. The candidate will interact and collaborate closely with other laboratory-based scientists across the Center, Armstrong and Stegmaier labs and Dana-Farber Cancer Institute. Requirements Help to plan and execute pre-clinical in vivo mouse studies with...

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The Marasco lab within the Department of Cancer Immunology and Virology is seeking a highly motivated and experienced individual to join our team as a Senior Research Technician who will perform cancer immunotherapy bench research including in vitro molecular biology and immunology studies and in vivo small animal...